Are there individuals with the Fragile X premutation and are unaware of their genetic condition?

Yes, Fragile X conditions are inherited genetically, and it is passed through generations often unknowingly.

How many individuals are carriers of the FMR1 premutation?  According to a 2012 study by the CDC, the frequency of Fragile X premutation in the U.S. is as follows:

  • 1 in 151 females, or about 1 million women
  • 1 in 468 males, or about 320,000 men

To find out more: