Premutation
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      1. Fragile X Knowledge Center
      2. FXTAS
      3. Premutation

      How common is Fragile X - associated tremor/ataxia syndrome (FXTAS)?

      Current estimates suggest that about 30-40% of males with the FMR1 premutation over 50 years of age who are within families already known to have someone with Fragile X will ultimately exhibit some features of Fragile X - associated tremor/ataxia syndrome (FXTAS). Studies of females have found that about 8-16% of females with the FMR1 premutation, within families already known to have someone with a Fragile X condition, develop some FXTAS symptoms. The symptoms in females tend to be milder.

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