I am preparing for a surgical procedure and am looking for information on anesthesia for an individual with the Fragile X premutation.

There is a great need for research to clarify which anesthesia is the least toxic to the aging brain and we do not know this answer yet. The link below is a publication titled, "General Anesthesia Use in Fragile X Spectrum Disorders". We suggest sharing this publication with your healthcare provider to help guide the treatment plan discussion.

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215737/

Dr. Randi Hagerman, Medical Director of the UC Davis MIND Institute Fragile X Research and Treatment Center, presented at the 18th NFXF International Fragile X Conference on the topic of Premutation Concerns. View the presentation and the panel discussion that followed at the links below:

• https://fragilex.org/blog/premutation-concerns/
• https://fragilex.org/webinar/premutation-panel-conferen/