At this time, there are no clinically established successful therapies to regain ovarian function for women with FXPOI. However, there are important strategies to minimize the clinical and emotional consequences associated with ovarian insufficiency.
- Emotional well-being. A diagnosis of POI can be emotionally devastating for a woman who has not completed, or even started, family planning. Even for a woman who was not planning a pregnancy, the loss of fertility can lead to emotional distress.
- Hormone Replacement Therapy (HRT). Given that bone density continues to accrue during the 20s and 30s, peak bone mass is an important concern for women with POI. The American Society for Reproductive Medicine and the International Menopause Society recommend hormone replacement therapy for women with POI.
- Bone mineral density. General guidelines to minimize bone loss include weight-bearing physical activity and a healthy balanced diet.
- Family planning. Women with FXPOI should not assume infertility, and contraception is recommended for those not wanting to conceive a pregnancy.
- Parenthood. There are several parenthood options available to women with FXPOI, depending on the needs of the woman.